You can tolerate that combination, but lower gears would be better. I have been "tolerating" my 4.11's, 33" tires, and NV3550 5-speed since 2003. It's fine in the flatlands of Silicon Valley, but I have to use 4th gear, sometimes 3rd gear, when I'm cruising the highways in the Sierras. I am flogging my 4.0L to the floor all the time, keeping up with my four wheeling buddies in Toyota's and Ford pickups and a supercharged JK.
Now however, I want to tow a small (less than 1000lbs) trailer, so I'm planning 4.88's and a brake upgrade to the Vanco 16" kit. Without plans for towing a trailer, it would be 4.56 gears. After 8 years on 33's, I don't feel the need for bigger tires.