Some folks find the weber difficult to tune & maintain, but they seem to work OK if set up correctly (right fuel pressure, etc).
I have a MC2100 that works great, idles at crazy lean angles, will easily bark 31s w/ stock gears & gets 15-17MPG in town.
There are some big fans of Holley carbs, too. I've run them on plenty of muscle cars, but they tend to be a bit pricey & are hard to find in the junk yard.
The MC only cost me 90 bucks to buy & rebuild. 3+ years later, I haven't had to touch it once.