I found about a year or so ago that I've been adjusting my door mirrors the wrong way for all the time I've been driving. Once I adjusted them properly, I no longer have a blind spot (well, more precisely, I have a blind spot but it is in a spot relative to the Jeep that isn't dangerous). This talks about it:
How To: Adjust Your Mirrors to Avoid Blind Spots - Feature - Car and Driver, but here is the process I actually use:
1.) Driver side - sit in normal driving position and then lean my head all the way to the left until my temple is touching the driver side door glass. Then adjust driver mirror horizontally to just barely show the side of the Jeep and vertically so the horizon is centered in my view.
2.) Passenger side - sit in normal driving position and then lean by body to the right until I am as close to the centerline of the Jeep as I reasonably can be. Then adjust driver mirror horizontally to just barely show the side of the Jeep and vertically so the horizon is centered in my view.
3.) switch power mirror control to neutral position so it doesn't get bumped.
Now, as mentioned in the article, this is a very different view of the road out the mirrors compared to what it used to be, but I find that on the sides without turning my head at all, the 'blind spot' is now roughly the size of a Smart car (i.e. any bigger and I will see at least part of the other vehicle in either peripheral vision or mirror). There is also technically a blind spot far, far behind, but it's far enough behind that it's really not a problem.
The way I used to adjust mirrors (and as far as I know, everyone else seems to do this, as every time I get in another vehicle, they seem adjusted this way) - sit normal and then adjust both mirrors so the edge of your own vehicle is just barely in view on the edge of the mirror. Never again for me!